SETTLE

Immunotherapeutic product for treating Endometritis

Description:

Settle is a USDA-approved immunotherapeutic that is recommended as an aid in the treatment of
endometritis caused by Streptococcus zooepidemicus.
The product is approved for both intravenous and intrauterine administration.
Settle is the world’s first and only immunotherapeutic licensed to treat endometritis. Studies have shown that a single dose of Settle can help resolve a broodmare’s uterine infection and the damaging inflammation it causes.

Composition

Settle is a USDA-approved immunotherapeutic that is recommended as an aid in the treatment of endometritis caused by Streptococcus zooepidemicus.

The product is approved for both intravenous and intrauterine administration.

Settle is the world’s first and only immunotherapeutic licensed to treat endometritis. Studies have shown that a single dose of Settle can help resolve a broodmare’s uterine infection and the damaging inflammation it causes.

Indications

The only approved immune-modulator for:

  • Treatment of Uterine infections due to Streptococcus Zooepidemicus in the mare,
  • Enhancement bacterial clearance (University of Kentucky – Gluck Equine Research Centre),
  • Induction efficient involution of the uterus resulting in the ability to prepare the mare for early breeding (foal heat) (Fumuso et al. 2003),
  • Shortening days to ovulation (11 days) (University of Kentucky –Gluck Equine Research
    Centre)

Direction for use:

It is administered as a 1.5 mL dose by intrauterine instillation with a sterile catheter or by
intravenous injection into the jugular vein during the early estrus period.
Treatment may be repeated at subsequent natural or induced estrus periods.

The brief description of the medicine is for information purpose only. Read the content of the package leaflet carefully before use. If you have any further questions, ask your veterinarian or pharmacist.

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